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SNP Calling Pipeline — Genomic Integrity of Reprogrammed Cells

About

This repository contains R scripts for SNP calling and Copy Number Variation (CNV) analysis, developed to evaluate the genomic integrity of human reprogrammed cells (iPSCs).

Developed during MSc M1 internship at CRTI, UMR 1064, Nantes Université (dir. L. David), contributing to work published in Gaignerie et al., Scientific Reports, 2018.

Key analyses

  • SNP calling from sequencing data
  • CNV detection across reprogrammed vs. parental cells
  • Genomic integrity assessment of iPSC lines

Tools & dependencies

  • R / Bioconductor
  • See script headers for package requirements

Author

Valentin FRANCOIS--CAMPION — GitHub

About

SNP calling pipeline to assess genomic integrity of reprogrammed cells — Copy Number Variation (CNV) analysis · R

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