Leaving this here as part of the paper documentation. HMF want to analyse an Illumina WGS sample with DRAGEN 4.x (4.5 preferred, 4.4.6 also acceptable) to serve as a reference for matching Ultima and SBX sequencing data processed with oncoanalyser.
The selected sample is HG008 aka Cancer Genome in a Bottle from NIST:
What's included — 48 files, ~150 GB total: HG008T (tumour, ~107 GB) and HG008R (normal, ~43 GB). Illumina NovaSeq 6000, paired-end 2×150 bp, three flowcells × four lanes per sample. These were downsampled at Hartwig using the same procedure we apply to our other benchmark datasets, so they are directly comparable to those.
How to download — urls.txt contains presigned links; no Google account needed. We recommend:
aria2c -i urls.txt -x 4 -j 4 -c -d ./hg008_fastq
This downloads in parallel and resumes if interrupted. Full instructions, including checksum verification against manifest.tsv, are in README.txt.
Presigned URLs provided to @scwatts via Slack (or will be in a minute!).
Leaving this here as part of the paper documentation. HMF want to analyse an Illumina WGS sample with DRAGEN 4.x (4.5 preferred, 4.4.6 also acceptable) to serve as a reference for matching Ultima and SBX sequencing data processed with oncoanalyser.
The selected sample is
HG008aka Cancer Genome in a Bottle from NIST:Presigned URLs provided to @scwatts via Slack (or will be in a minute!).